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Review Article
2019
:10;
56
doi:
10.25259/SNI-34-2019
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T1–T2 disc herniation: Report of four cases and review of the literature

Pars Advanced and Minimally Invasive Medical Manners Research Center, Iran University of Medical Sciences, Tehran, Iran
Corresponding author: Naser Asgari, Pars Advanced and Minimally Invasive Medical Manners Research Center, Num. 10, Rastak St., Keshawarz Blvd., Tehran, Iran. nvasgari@gmail.com
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Abstract

Background:

Symptomatic T1–T2 disc herniations are rare and, in most cases, are located posterolaterally. Posterior approaches may utilize transfacet pedicle-sparing techniques, while the less frequent central/anterolateral discs may warrant anterior surgery.

Case Description:

Here, we reviewed four cases of symptomatic T1–T2 disc herniations; two patients were paraparetic due to central discs and underwent anterior surgery utilizing a cage construct. The latter two cases had posterolateral discs contributing to a Brown-Sequard syndrome and radiculopathy, respectively; one patient required a transfacet pedicle-sparing procedure, while the second case was managed conservatively. All surgically treated patients recovered fully.

Conclusions:

We reviewed 4 cervical T1–T2 disc herniations; two central/anterolateral lesions warranting anterior surgical approaches/cages, and 2 lateral discs treated with a posterolateral transfacet, pedicle-sparing procedure and no surgery respectively. Follow-up magnetic resonance studies documented full resolution for the patient with radiculopathy and a posterolateral disc.

Keywords

Disc herniation
spontaneous resolution
sternal splitting approach
T1–T2 disc space
thoracic disc
upper thoracic disc herniation

INTRODUCTION

Thoracic disc herniations make up 0.25%–0.75% of all disc ruptures.[3,6,19,28,30,34] Most thoracic disc herniations occur below the T8 level, and the majority are found at T11–T12.[3,6,19,28,30,34] T1–T2 discs account for only approximately 1–3% of all thoracic discs. The first reported case was in 1945; since then, only 31 additional cases have been published.[1,2,4,5,7,8,11-15,17,18,25,26,29,32,33,35-37] T1–T2 disc herniation can present with either radiculopathy or myelopathy.

In this article, we reviewed these 32 prior cases of T1–T2 disc herniations and added our four cases. We focused on the clinical presentation, e.g. T1–T2 myelopathy and/or radiculopathy, magnetic resonance (MR) localization (anterior/anterolateral/lateral posterior), and optimal surgical management.

METHOD

Cases 1 and 2

The four cases of T1–T2 discs included two females and two males who ranged in the age group from 36 to 67 years (average: 47 years). Two females aged 67 and 48 years presented with acute cord infarction and paraparesis, respectively; the modified Japanese Orthopaedic Association (JOA) score for thoracic myelopathy (maximum 11) was 6 and the second patient was 7 [Table 1]. MR studies documented a soft central disc in one patient, and a calcified central disc in the second [Figures 1 and 2]. Both were approached anteriorly with low cervical-suprasternal approaches and accompanied by cage application.

Table 1: The details of 36 cases with T1–T2 disc herniation.
Figure 1: (a) T2-weighted sagittal image demonstrating a disc herniation at T1–T2 level with considerable cord compression. (b) Axial view showing the central location of the disc. (c) Manubrium line and cervicothoracic (CT) angle on T2-weight magnetic resonance imaging (MRI): manubrium line intersects T2 vertebral body near to T2–T3 disc, CT angle is about 38°. (d) Chest X-ray showing that T1–T2 disc space is far enough above biclavicular line. (e) Showing removal of the sequestrated disc fragment. (f) After placement of peek cage, note brachiocephalic vein at lower border of the scene. (g) Post-operative CT AP X-ray: shows the cage in T1–T2 disc space. (f) Postoperative T1-weighted MRI, at 3-year follow-up, note clearance of the cord. (i) Postoperative T2-weighted MRI demonstrates the cage in T1–T2 interspace.
Figure 2: (a) T2-weighted sagittal magnetic resonance imaging (MRI) of the second case showing a hard disc at T1–T2 level. (b) The disc space is a little bit above the manubrium line and cervicothoracic (CT) angle is 27°. (c) Reconstructed sagittal computed tomography (CT) scan of the CT region showing T1–T2 hard disc, indicating that the compression, also note that CT angle is 10°. (d) Chest X-ray shows that T1–T2 disc is a few mm above the manubrium. (e) Intraoperative clearance of the disc space from both hard disc and osteophytes. (f) After placement of a large cage. (g) Plain CT radiograph showing that the cage is located at bicalvicular line. (h) Postoperative T2-weighted MRI: showing appropriate decompression of the spinal cord at T1–T2 level.

Cases 3 and 4

Cases 3 and 4, respectively exhibited, a Brown-Sequard syndrome and radiculopathy alone. For the former patient, cervicothoracic MRI showed a left centro-laterally disc at the T1–T2 level. This was excised utilizing a transfacet pedicle-sparing left-sided approach with left-sided T1–T3 pedicle screw fixation to avoid instability [Figure 3]. The fourth patient had an MR left-sided laterally located extruded disc at the T1–T2 level managed nonsurgically [Figure 4a and b].

Figure 3: (a) T2-weighted sagittal magnetic resonance imaging (MRI) shows T1–T2 disc herniation. (b) Sagittal cervical fat saturated MRI shows the same. (c) Axial T2-weighted MRI shows a hyperintense disc on the left side. (d) Three-dimensional cervical computed tomography (CT) scan shows T1–T2 and T3 screw rod fixation on the left side. (e) Axial CT scan shows a pedicle screw in an upper thoracic vertebra.
Figure 4: (a) T2-weighted sagittal magnetic resonance imaging shows a T1–T2 extruded disc migrated up. (b) Axial view shows the posterolaterally located disc is on the left side. (c) T2-weighted sagittal image shows complete resolution of the disc at 5-month follow-up. (d) Axial T2-weighted axial view also confirms disappearance of the disc.

RESULT

The surgically treated patients all markedly recovered over an average of 3.87 years’ follow-up (range: 6 months–7 years). Postoperative MR imaging (MRI) studies in the first two patients showed adequate cord decompression following placement of T1–T2 anterior interbody cages [Figures 1 and 2]. The third patient undergoing a transfacet pedicle-sparing left-sided approach had a postoperative three-dimensional computed tomography scans showing adequate root decompression and screw placement screws [Figures 3e and d]. For the fourth patient, the sequestrated disc disappeared 5 months later [Figures 4c and d]. Outcomes were based on the modified JOA scores for the three patients with thoracic myelopathy and their scores were 10, 11, and 11, respectively, while the visual analog scale for the fourth patient was 0.

DISCUSSION

Frequency of T1–T2 discs

Symptomatic disc herniation in the upper thoracic spine from T1 to T4 is rare, with most occurring at T1–T2 levels[3,6,19,28,30,34] [Table 1]. We added our cases (four cases) of T1–T2 disc herniations to those 32 cases found in the literature.[1,2,4,5,7,8,10-17,21,24-26,29,31-33,35-37] There were 24 males and 12 females averaging 49.1 years of age (range 23–72 years of age) [Table 2]. Most T1–T2 discs were posterolateral in location (25 cases); only 11 were purely central or centrolateral. In one case, a central disc fragment extended through the dura.[15] Patients with thoracic discs typically present with neck pain (i.e. 24/36 patients).[1,2,4,5,7-9,11-15,17,18,21,24-26,29,31-33,35-37]

Table 2: Patients demographic data and common clinical features of the corresponding location at which they generate.

Diagnosis of T1–T2 discs and therapeutic intervention

MRI best documents soft T1–T2 thoracic discs, while computed tomography is typically optimal for calcified herniations.

Conservative versus surgical treatment for T1–T2 discs

Conservative treatments are appropriate for T1–T2 discs resulting in just mild radiculopathy (e.g. posterolateral discs) and, in some cases, spontaneously resolved (2 of 36 cases).

Surgery for T1–T2 posterolateral herniated discs may require transfacet pedicle-sparing decompression with pedicle screw fixation.[4,6,27,30,34] However, for central T1–T2 disc herniations, resulting in significant myelopathy, anterior surgery may be warranted (e.g., the low cervical-manubrium method and/or limited sternal splitting procedures).[6,20,22,23,27,34]

CONCLUSIONS

T1–T2 thoracic disc herniations are an extremely rare, and optimal results depend on the central and centrolateral location of the discs and the operative/nonoperative choices were made based on the clinical presentation.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understand that her name and initial will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

REFERENCES

  1. , , . Protrusions of thoracic intervertebral disks. Neurology. 1956;6:1-10
    [Google Scholar]
  2. , , , , . High thoracic disc herniation. Neurosurgery. 1986;19:449-51
    [Google Scholar]
  3. , , . Thoracic intervertebral disc protrusion:A clinical study. J Neurosurg. 1960;17:418-30
    [Google Scholar]
  4. , , , , , . Early experience treating thoracic disc herniations using a modified transfacet pedicle-sparing decompression and fusion. J Neurosurg Spine. 2010;12:221-31
    [Google Scholar]
  5. , , , , , . Magnetic resonance image findings and surgical considerations in T1-2 disc herniation. Can J Neurol Sci. 2003;30:152-4
    [Google Scholar]
  6. , , , . Diagnosis and treatment of thoracic intervertebral disc protrusions. J Neurol Neurosurg Psychiatry. 1971;34:68-77
    [Google Scholar]
  7. , . Herniated thoracic disc at T1-2 level associated with horner's syndrome. Case report. J Neurosurg. 1978;48:128-30
    [Google Scholar]
  8. , , , , , . T1-T2 disc herniation:Two cases. Rev Chir Orthop Reparatrice Appar Mot. 2006;92:715-8
    [Google Scholar]
  9. , , , , , . A rare case of T1-2 thoracic disc herniation mimicking cervical radiculopathy. Int J Spine Surg. 2017;11:30
    [Google Scholar]
  10. , , , . Protrusion of the first thoracic disk. Surg Neurol. 1991;35:329-31
    [Google Scholar]
  11. , . Extruded upper thoracic disc causing horner's syndrome:Report of a case. Med Ann Dist Columbia. 1968;37:541-2
    [Google Scholar]
  12. , . Experience with ruptured T1-T2 discs. J Indiana State Med Assoc. 1980;73:598-9
    [Google Scholar]
  13. , , , . Ruptured thoracic discs. Yale J Biol Med. 1955;28:322-30
    [Google Scholar]
  14. , , , , , , . T1 radiculopathy caused by intervertebral disc herniation:Symptomatic and neurological features. J Orthop Sci. 2009;14:103-6
    [Google Scholar]
  15. , , , . Upper thoracic spine arthroplasty via the anterior approach. J Neurosurg Spine. 2010;13:240-5
    [Google Scholar]
  16. , , . First thoracic disc protrusion. Spine (Phila Pa 1976). 1986;11:499-501
    [Google Scholar]
  17. , , , . Postfixed brachial plexus radiculopathy due to thoracic disc herniation in a collegiate wrestler:A case report. J Athl Train. 2013;48:710-5
    [Google Scholar]
  18. , , , , . Horner's syndrome secondary to herniated disc at T1--T2. AJR Am J Roentgenol. 1980;134:184-5
    [Google Scholar]
  19. , . Thoracic intervertebral disc prolapse with spinal cord compression. J Neurol Neurosurg Psychiatry. 1952;15:227-41
    [Google Scholar]
  20. , , , . Anterior approach to the cervicothoracic junction by unilateral or bilateral manubriotomy. A report of five cases. J Bone Joint Surg Am. 2002;84-A:1013-7
    [Google Scholar]
  21. , , . Disc herniation at T1-2. Report of four cases and literature review. J Neurosurg. 1998;88:148-50
    [Google Scholar]
  22. , , . Thoracic disc herniations:Transthoracic, lateral, or posterolateral approach?A review. Surg Neurol. 1998;49:599-606
    [Google Scholar]
  23. , , , , , , . Sternal split approach to the cervicothoracic junction in children. Spine (Phila Pa 1976). 2005;30:E305-10
    [Google Scholar]
  24. , , . First thoracic disc herniation with myelopathy. Eur Spine J. 1995;4:366-7
    [Google Scholar]
  25. , , , , . Intradural disc herniation at the T1-T2 level. Croat Med J. 2001;42:193-5
    [Google Scholar]
  26. , . Arbit E. A surgical approach through the pedicle to protruded thoracic discs. J Neurosurg. 1978;48:768-72
    [Google Scholar]
  27. , , . Spontaneous resolution of sequestrated lumbar disc herniation:A prospective cohort study. J Glob Spine J. 2016;6(Suppl 1):s-0036
    [Google Scholar]
  28. , . Thoracic disc herniation:20 years experience in 82 cases. J Glob Spine J. 2016;6(Suppl 1):s-0036
    [Google Scholar]
  29. , , , , . The anterior approach to high thoracic (T1-T2) disc herniation. Br J Neurosurg. 1993;7:189-92
    [Google Scholar]
  30. , , . Thoracic disc herniation:Operative approaches and results. Neurosurgery. 1983;12:303-5
    [Google Scholar]
  31. , , , . Approaching the upper thoracic vertebrae without sternotomy or thoracotomy:A radiographic analysis with clinical application. Spine (Phila Pa 1976). 2000;25:910-6
    [Google Scholar]
  32. , , , , , , . Surgical treatment of t1-2 disc herniation with t1 radiculopathy:A case report with review of the literature. Asian Spine J. 2012;6:199-202
    [Google Scholar]
  33. , , , , . Horner's syndrome secondary to intervertebral disc herniation at the level of T1-2. BMJ Case Rep. 2014;2014 bcr2014204820
  34. , , , , , . Experience in the surgical management of 82 symptomatic herniated thoracic discs and review of the literature. J Neurosurg. 1998;88:623-33
    [Google Scholar]
  35. , , . Multiple protrusions of intervertebral disks in the upper thoracic region:Report of case. Proc Staff Meet Mayo Clin. 1954;29:375-8
    [Google Scholar]
  36. , , , , , . T1-2 disc herniation following an en bloc cervical laminoplasty. J Orthop Sci. 2002;7:495-7
    [Google Scholar]
  37. , , . Herniated thoracic disc at T1-T2 with paraparesis. Transthoracic excision and fusion, case report with 4-year follow-up. Spine (Phila Pa 1976). 1993;18:782-4
    [Google Scholar]
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