Severe hypotension with loss of motor evoked potentials during cervical surgery prompting immediate cardiovascular resuscitation

Daniel C. Kim; Ethan J. Boyd; Thomas A. Boyd; Hannah E. Granger; Richard P. Menger

doi:10.25259/SNI_336_2021

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Case Report

2021

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281

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10.25259/SNI_336_2021

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Severe hypotension with loss of motor evoked potentials during cervical surgery prompting immediate cardiovascular resuscitation

Daniel C. Kim¹, Ethan J. Boyd², Thomas A. Boyd², Hannah E. Granger², Richard P. Menger²

1Department of Orthopaedic Surgery, Twin Cities, Minneapolis, Minnesota, United States.

2Department of Neurosurgery, University of South Alabama Health University Hospital, Mobile, Alabama, United States.

*Corresponding author: Hannah Granger, Department of Neurosurgery, University of South Alabama Health University Hospital, Mobile, Alabama, United States. heg1822@jagmail.southalabama.edu

Received: 2021-04-04, Accepted: 2021-05-26, Published: 2021-06-14

Licence

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Kim DC, Boyd EJ, Boyd TA, Granger HE, Menger RP. Severe hypotension with loss of motor evoked potentials during cervical surgery prompting immediate cardiovascular resuscitation. Surg Neurol Int 2021;12:281.

Abstract

Background:

Intraoperative neuromonitoring (IONM) is a well-established adjunct to spinal surgery to ensure safety of the neural elements.IONM has extremely high sensitivity and specificity for impending neurologic damage. In very rare instances, hypoperfusion of the cord may lead to a loss of IONM modalities that may be reversed if blood pressure issues responsible for the drop out of potentials are immediately addressed.

Case Description:

The authors describe a case in which IONM documented hypoperfusion of the cord intraoperatively due to hypotension. Recognition of this problem and reversal of the hypotension resulted in normalization of postoperative function.

Conclusion:

The use of IONM allowed for quick recognition of an impending neurological insult during spinal deformity surgery. Prompt response to signaling changes allowed for the correction of hypotension and favorable neurologic outcome.

Keywords

Hypotension

Multimodal neuromonitoring

Neurosurgery

Spinal deformity surgery

Spine

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INTRODUCTION

Intraoperative neuromonitoring (IONM) is a well-established adjunct to spinal surgery.[2] When combined with clinical analysis, IONM has sensitivity and specificity for an impending neurologic event of nearly 100%.[4,7,9] Here, we present a clinical case demonstrating the safety value of such real-time data, preventing potentially catastrophic neurologic injury secondary to hypotension/cardiovascular collapse.

CASE REPORT

An elderly female presented with a trauma-induced, unstable Type 2 odontoid fracture. The patient on presentation was found to have a traumatic aortic dissection emergently treated with endovascular stenting. Next, she underwent a posterior C1-C2 instrumented fusion. Manual reduction of the fracture with Mayfield pinning was performed prior to incision. The C1-C2 fusion was performed with C1 lateral-mass and C2 pars screws. The fusion was performed without significant changes on electromyography, somatosensory evoked protentional, and transcranial motor evoked potential (tcMEP) monitoring.

Post instrumentation IONM changes

Post-instrumentation, during decortication for bone grafting and fusion, a routine tcMEP showed a complete loss of right lower extremity MEP. An immediate check of the blood pressure was performed; it could not be obtained. The repeat tcMEP now showed loss of bilateral lower extremity signals. A repeat check of the blood pressure, again, showed no data. At this point, the lack of MEP was attributed to hypoperfusion of the Artery of Adamkiewicz secondary to global hypoperfusion. Immediate resuscitation was initiated with vasopressors and a repeat blood pressure increased to 60 mmHg systolic/20 mmHg diastolic. The wound was emergently closed and the patient was flipped supine. A cardiac code was called and the blood pressure returned to normal, along with bilateral lower extremity tcMEP. The patient was intact on the immediate post-operative examination. The etiology of the patient’s blood pressure loss, responsible for the drop-out of MEP, was never clear.

DISCUSSION

Neuromonitoring signal changes may commonly occur (28%) during deformity surgery.[1,3,6,8] With immediate recognition of IONM changes, and appropriate resuscitative efforts, the overall rate of new neurological deficits is low.[3,5,10,11]

Here, the patient’s neurologic insult occurred due to global hypoperfusion, which lead to transient ischemia of the cord. The etiology of the hypoperfusion in this case remains unclear, as the patient did not exhibit electrocardiogram changes during or after the case.

In this case, the most critical maneuver was recognition of MEP changes and the total loss of perfusion (loss of blood pressure), instituting vasopressors, closing, turning the patient supine, and providing cardiac resuscitation.

CONCLUSION

The use of IONM during spinal deformity surgery allowed for prompt recognition of loss of MEP and blood pressure allowing for immediate cardiac resuscitation and reversal of the impending neurological injury.

Declaration of patient consent

Patient’s consent not required as patients identity is not disclosed or compromised.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

REFERENCES

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[Google Scholar]
Vitale MG, Skaggs DL, Pace GI, Wright ML, Matsumoto H, Anderson RC, . Best practices in intraoperative neuromonitoring in spine deformity surgery: Development of an intraoperative checklist to optimize response. Spine Deform. 2014;2:333-9.
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Yoshida G, Ando M, Imagama S, Kawabata S, Yamada K, Kanchiku T, . Alert timing and corresponding intervention with intraoperative spinal cord monitoring for high-risk spinal surgery. Spine (Phila Pa 1976). 2019;44:E470-9.
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INTRODUCTION

CASE REPORT

Post instrumentation IONM changes

DISCUSSION

CONCLUSION

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[1] Ferguson J, Hwang SW, Tataryn Z, Samdani AF. Neuromonitoring changes in pediatric spinal deformity surgery: A single-institution experience. J Neurosurg Pediatr. 2014;13:247-54.
[Google Scholar]

[2] Laratta JL, Ha A, Shillingford JN, Makhni MC, Lombardi JM, Thuet E, . Neuromonitoring in spinal deformity surgery: A multimodality approach. Global Spine J. 2018;8:68-77.
[Google Scholar]

[3] Lewis SJ, Wong IH, Strantzas S, Holmes LM, Vreugdenhil I, Bensky H, . Responding to intraoperative neuromonitoring changes during pediatric coronal spinal deformity surgery. Global Spine J. 2019;9:15S-21S.
[Google Scholar]

[4] Quraishi NA, Lewis SJ, Kelleher MO, Sarjeant R, Rampersaud YR, Fehlings MG. Intraoperative multimodality monitoring in adult spinal deformity: Analysis of a prospective series of one hundred two cases with independent evaluation. Spine (Phila Pa 1976). 2009;34:1504-12.
[Google Scholar]

[5] Romstöck J, Strauss C, Fahlbusch R. Continuous electromyography monitoring of motor cranial nerves during cerebellopontine angle surgery. J Neurosurg. 2000;93:586-93.
[Google Scholar]

[6] Schwartz DM, Auerbach JD, Dormans JP, Flynn J, Drummond DS, Bowe JA, . Neurophysiological detection of impending spinal cord injury during scoliosis surgery. J Bone Joint Surg Am. 2007;89:2440-9.
[Google Scholar]

[7] Thuet ED, Winscher JC, Padberg AM, Bridwell KH, Lenke LG, Dobbs MB, . Validity and reliability of intraoperative monitoring in pediatric spinal deformity surgery: A 23-year experience of 3436 surgical cases. Spine (Phila Pa 1976). 2010;35:1880-6.
[Google Scholar]

[8] Vitale MG, Moore DW, Matsumoto H, Emerson RG, Booker WA, Gomez JA, . Risk factors for spinal cord injury during surgery for spinal deformity. J Bone Joint Surg Am. 2010;92:64-71.
[Google Scholar]

[9] Vitale MG, Skaggs DL, Pace GI, Wright ML, Matsumoto H, Anderson RC, . Best practices in intraoperative neuromonitoring in spine deformity surgery: Development of an intraoperative checklist to optimize response. Spine Deform. 2014;2:333-9.
[Google Scholar]

[10] Yoshida G, Ando M, Imagama S, Kawabata S, Yamada K, Kanchiku T, . Alert timing and corresponding intervention with intraoperative spinal cord monitoring for high-risk spinal surgery. Spine (Phila Pa 1976). 2019;44:E470-9.
[Google Scholar]

[11] Ziewacz JE, Berven SH, Mummaneni VP, Tu TH, Akinbo OC, Lyon R, . The design, development, and implementation of a checklist for intraoperative neuromonitoring changes. Neurosurg Focus. 2012;33:E11.
[Google Scholar]