Anterior cervical spine surgical complications: Safety comparison between teacher and student

INTRODUCTION

Using the anterior approach to the cervical spine, many spinal surgeons perform anterior cervical discectomy and fusion (ACDF), anterior cervical discectomy (ACD) without fusion, anterior cervical corpectomy and fusion, anterior cervical discectomy and arthroplasty (ACDA), or hybrid surgeries.[2,7,8]

One study documented an average 137,000 ACDF performed/year in the U.S. between 2006 and 2013.[9]

Despite its widespread use, the anterior approach is not devoid of potential serious complications.

Here, we evaluated whether the postoperative complication rates following anterior cervical surgery varied based on the surgeons’ years of practice: senior neurosurgeons (SNs) (SN, with more than 30 years of experience) versus novice neurosurgeons (NNs) (NN, with <5 years of training with the former surgeons).

MATERIALS AND METHODS

This was a retrospective study on complications rates obtained from medical records (follow-up time of 1 year) of patients undergoing (through a right-sided anterior cervical spine approach) ACD (1 patient), ACDF (105 patients), and ACDA (4 patients).

The procedures were performed from 2013 to 2020 (with 0-Arm Guidance at our institution, IRCCS “Istituto Ortopedico Galeazzi”) by either a SN versus a NN. Data were obtained from admission/discharge notes, clinical diaries, operative summaries, follow-up visits, and phone calls.

Data of interest included patients’ age and symptoms, radiological diagnosis, type of surgery (ACDF, ACD, and ACDA), operative time, and peri/postoperative complications.

Based on a combination of clinical and radiological features, patients were divided into six groups [Table 1].

Table 1:: Diagnostic classification based on radiological (presence or absence of disc herniation/spondylosis/vertebral instability) and clinical features (cervicobrachialgia, signs of myelopathy).

Clinical parameters

Patients in the SN’ and NN’ groups, respectively, averaged 57 (standard deviation [SD] = 13.36) and 54 (SD = 14.69) years of age and exhibited comparable degrees of radiculopathy and/or myelopathy. Mean operative times for the two cohorts were evaluated and compared utilizing Mann– Whitney U-test; surgical procedure durations ranged from 41 to 161 min (mean = 83.28, SD = 26.5) and from 60 to 158 min (mean = 97.30, SD = 20.6) for the SN and NN, respectively [Table 2]. To test whether the two cohorts were different concerning group composition, Pearson’s Chi-square test was adopted: after performing calculations, no statistically significant difference was found between the two, but NN cohort registered a significantly greater mean operative time when confronted with SN [Figure 1].

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Figure 1:: Distribution of patients between the two cohorts based on group’s diagnosis. Groups are specified on Table 1.

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Table 2:: Total surgical duration and most frequent diagnosis of the two cohorts and direct comparison.

RESULTS

The cumulative complication rate was 15.4% (17/110) that was similar for both cohorts, 9 in SN (15.7%) versus 8 in NN cohort (15.09%) [Table 3 and Figure 2]. The most frequent complication was dysphagia, occurring equally in both groups: 4/57 versus 4/53, respectively. Postsurgical dysphonia was present in 2.7% of all patients, and there was no statistically significant difference between the two groups (Fisher’s exact test P = 0.53). Intraoperative unintended durotomy occurred in 3 out of 110 patients (2.7%) without any statistically significant difference between the two cohorts (Fisher’s exact test P = 0.53). Hyposthenia was encountered in 2 out of 110 patients, 1 in each group. Hypoesthesia was present in only in 1 patient (0.9% of all) in the NN cohort.

Table 3:: Complication frequencies (with relative percentages) of ACD, ACDF, and ACDA surgical procedures.

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Figure 2:: Complications’ frequency in the two cohorts. DSG: Dysphagia, DSP: Dysphonia, UD: Unintended durotomy, HS: Hyposthenia, HE: Hypoesthesia.

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DISCUSSION

Epstein reported morbidity rates of ACD and ACDF spanning from 13.2% to 19.3%.[4] The most common complications included dysphagia, symptomatic recurrent laryngeal nerve palsy, Horner’s syndrome, cerebrospinal fluid leak, postoperative hematoma, instrument mechanical failure, esophageal perforation, worsening of preexisting myelopathy, and nerve root injury.[1,4,5,10] Specifically, Horner’s syndromes were more likely to occur with surgery at the C5–C6 level due to the progressive lateral divergence of the longus colli muscles C3–C6 (rate 0.06–1.1%).[3,4] Notably, Huang et al. documented no significant differences with ACDF versus anterior cervical corpectomy in terms of hospital stay, neck and arm pain, fusion rates, and complications.[6] In their series, Tasiou et al. reported an incidence of 1.7% of dural leakage that could largely be avoided utilizing an operating microscope and a 1.7% of postoperative hematomas.[10]

CONCLUSION

In Epstein’s review, ACD and ACDF complication rates ranged from 13.2 to 19.3%.[4] In this study, we found that spinal surgeons’ years of experience proved not to be a critical factor in determining complication rates for these procedures.